Search results for "Eccrine sweat gland"

showing 3 items of 3 documents

Comparative cytokeratin analysis of sweat gland ducts and eccrine poromas.

1991

Human eccrine sweat gland ducts and benign and malignant eccrine poromas were studied for the expression of various cytokeratins (CK) and vimentin by applying immunoperoxidase and immunofluorescence microscopy to frozen or paraffin-embedded sections, and using two-dimensional gel electrophoresis and immunoblotting. In acrosyringia and dermal eccrine ducts, the luminal cells exhibited intense staining for CKs 1/10/11 and 19. The periluminal cell layers of acrosyringia contained CKs 1/10/11, while CK 5 was absent. In contrast, the basal cell layer of dermal ducts was only positive with the antibody against CK 5, i. e. a pattern resembling that seen in epidermal basal cells. CK 9 was detected …

AdultMalePathologymedicine.medical_specialtyVimentinDermatologyBiologyCytokeratinPoromaSweat glandKeratinmedicineHumansVimentinEccrine sweat glandSkinchemistry.chemical_classificationImmunoperoxidaseAdenoma Sweat GlandGeneral MedicineMiddle Agedmedicine.diseaseImmunohistochemistryStainingSweat GlandsSweat Gland Neoplasmsmedicine.anatomical_structurechemistrybiology.proteinKeratinsFemaleArchives of dermatological research
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Ultrastructural Pathology of Eccrine Sweat Gland Epithelial Cells in Globoid Cell Leukodystrophy

1993

Three of four children were recognized by deficient β-galactocerebrosidase activities as having globoid cell leukodystrophy inclusions in sweat gland epithelial cells, similar in ultrastructure to those seen in Schwann cells. This observation in globoid cell leukodystrophy emphasizes the need to include sweat gland epithelial cells in examinations of skin in globoid cell leukodystrophy, as well as in any neurometabolic disorder. ( J Child Neurol 1993;8:171-174).

MalePathologymedicine.medical_specialtyBiopsyCellEccrine GlandsBiologyEpitheliumInclusion bodiesUltrastructural Pathology03 medical and health sciences0302 clinical medicine030225 pediatricsSweat glandmedicineHumansEccrine sweat glandChildSkinInclusion Bodiesintegumentary systemLeukodystrophyInfantLipid Metabolismmedicine.diseaseEpitheliumLeukodystrophy Globoid CellMicroscopy Electronmedicine.anatomical_structureChild PreschoolVacuolesPediatrics Perinatology and Child HealthUltrastructureFemaleNeurology (clinical)030217 neurology & neurosurgeryJournal of Child Neurology
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Significance of lipopigments with fingerprint profiles in eccrine sweat gland epithelial cells.

1995

Lipopigments with fingerprint profiles in eccrine sweat gland epithelial cells are regular findings in childhood NCL. They have also been described in adult NCL (ANCL) a few times, but not consistently. However, they have been considered nonspecific when not matched by similar abnormal profiles in noneccrine sweat gland epithelial cells. These conflicting reports may pose a diagnostic dilemma as outlined in the following 2 examples. Patient 1 is a 20-year-old man who developed severe tetraparesis and dementia over 2 years. Electroencephalogram was abnormal with epileptiform discharges. The patient died at age 21 years without autopsy ; no other relatives are known to have a similar disease.…

AdultMalemedicine.medical_specialtyPathologyAtaxiaAutopsyBiologyEccrine GlandsEpitheliumLipofuscinNeuronal Ceroid-LipofuscinosesSweat glandInternal medicinemedicineHumansEccrine sweat glandChildGenetics (clinical)Skinmedicine.diagnostic_testPigments BiologicalMiddle Agedmedicine.diseaseLipidsMicroscopy ElectronEndocrinologymedicine.anatomical_structureNeuronal ceroid lipofuscinosisFemalemedicine.symptomElectroretinographyRetinopathyAmerican journal of medical genetics
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